Research Associate - Center for Gene Therapy- Wein
- Nationwide Children's Hospital
- Columbus, OH
- Full Time
- 13 days ago
Salary
N/A
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Job Description
Overview:
Here, Diversity, Equity and Inclusion are integrated into our core values and practices. We are passionate about building, sustaining and evolving an inclusive and equitable environment. We are seeking individuals who live these values and want to share their experiences and efforts in support of our collective mission.
Ask anyone with a Nationwide Children’s badge what they do for a living. They’ll tell you it’s More Than a Job. It’s a calling. It’s a chance to use and grow your talent to make an impact that truly matters. Because here, we exist simply to help children everywhere.
Nationwide Children’s Hospital. A Place to Be Proud.Responsibilities:
The Wein Lab is focusing on Neuromuscular Disorders such as Duchenne Muscular dystrophy, which is a devastating disease leading to death of patients at age 20-30 years. Our lab developed an expertise in translational research, an emerging field which can be summarized as understanding the cause of a disease and learning from it in order to develop innovative therapeutic strategies. We are fully committed to continuing to integrate basic science and gene therapy skills in order to advance understanding and treatment of the muscular dystrophies. Our lab long term project focus on RNA and DNA editing and gene transfer as therapies for neuromuscular disorders, but it will also include more fundamental research on muscle function. In particular, our lab uses most recent technologies such as virus-mediated exon-skipping and the CRISPR/Cas9 genome editing tool. We are looking for a highly motivated research associate person who is energetic and intelligent to join our dynamic team. In particular, we are looking for someone with experience in molecular biology (qPCR, IF, WB), as well as mouse injection and dissection experiences for neuromuscular disorders. Experience in dissecting and mounting muscle tissue is preferred. No background in gene therapy is required, however the person should have a high interested in human genetics and diseases and should be eager to learn and work on the bench in an independent manner. Finally, our team relies on good teamwork and therefore, the candidate should be a good communicator and team player. The job description includes, but is not restricted to performing research experiments, maintaining records of experiments, preparing laboratory reports, analyzing data and preparing publications and grants applications.
Why Nationwide Children's Hospital?: The moment you walk through our doors, you feel it. When you meet our patient families, you believe it. And when you talk with anyone who works here, you want to be part of it. Welcome to Nationwide Children’s Hospital, Where Passion Meets Purpose.
Here, Diversity, Equity and Inclusion are integrated into our core values and practices. We are passionate about building, sustaining and evolving an inclusive and equitable environment. We are seeking individuals who live these values and want to share their experiences and efforts in support of our collective mission.
We’re 14,000 strong. And it takes every one of us to improve the lives of the kids we care for, and the kids around the world we’ll never meet. Kids who live healthier, fuller lives because of the knowledge we share. We know it takes a Collaborative Culture to deliver on our promise to provide the very best, innovative care and to foster new discoveries, made possible by the most groundbreaking research. Anywhere.
Ask anyone with a Nationwide Children’s badge what they do for a living. They’ll tell you it’s More Than a Job. It’s a calling. It’s a chance to use and grow your talent to make an impact that truly matters. Because here, we exist simply to help children everywhere.
Nationwide Children’s Hospital. A Place to Be Proud.
- Performs research experiments semi-independently or independently after training in accordance with protocols approved by the principal investigator. Such experiments may involve the use of laboratory animals or human subjects, any may require evening and/or weekend duties.
- Prepares and tests substrate, conducts assays, and prepares tissue cultures for use in research studies, as applicable. Collects muscle, blood and other samples as needed. Such activities may be performed independently and may require evening and weekend hours.
- Ensures accuracy of laboratory analytical procedures as required by specific research projects.
- Collects and controls experimental data; and maintains accurate daily logs of experiments including methods, results, and conclusions.
- Interprets the results of data analyses with input from the principal investigator.
- Assists the principal investigator in the preparation of scientific publications and grant proposals.
- Make recommendations about refinement and/or replacement of laboratory analytical procedures. Implements such refinements or new procedures with input from the principal investigator.
- Orders supplies needed to conduct research; maintains inventory of equipment and supplies; and assures that research equipment is in good working order.
- Collaborates in the preparation of research budgets, and monitors expenditure of funds to assure that studies are conducted within budgetary constraints.
- Instructs other laboratory workers and students in standard methods, practices, procedures, and equipment operations.
- Maintains a clean working area and performs general laboratory maintenance. Adheres to proper safety techniques and procedures.
- Performs miscellaneous related duties.
KNOWLEDGE , SKILLS AND ABILITIES REQUIRED
- Bachelor of Science degree with four to five year of laboratory research experience.Laboratory experience is requiredCoursework in dissection, muscle physiology and relevant research methods are desirable.
Minimum Physical Requirements:
- Percent of time spent on: 50% Preparing test substrates, conducting assays, preparing cultures25% Interpreting results of data analyses with PI/postdoctoral students.11% Miscellaneous paperwork associated with research10% Ordering supplies02% Preparation of budget02% Instructing other lab personnel
- 100% Kneeling / reaching100% Finger dexterity100% Talking / hearing / seeing 33% Lifting / carrying weight 0-20 pounds for 1-5 minutes
- The above list of duties is intended to describe the general nature and level of work performed by individuals assigned to this classification. It is not to be construed as an exhaustive list of duties performed by the individual so classified, nor is it intended to limit or modify the right of any supervisor to assign, direct, and control the work of employees under his/her supervision.
- EOE M/F/Disability/Vet
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